African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords	Funding Details
Scopus	2-s2.0-24644481854	Pharmacological evaluation of the central nervous system activity of Aframomum melegueta seed ext...	Umukoro S., Ashorobi R.B.	2005	Journal of Natural Remedies	5	2	None	Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria	Umukoro, S., Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria...	Objective: To study the effects of intraperitoneal injection of aqueous seed extract of Aframomum...	Aframomum melegueta; Anti-stereotypic; Anticonvulsant; Isoniazid; Methamphetamine; Pentobarbital;...	Aframomum melegueta extract; chlorpromazine; diazepam; isoniazid; methamphetamine; pentobarbital;...	None	View
Scopus	2-s2.0-33845241674	Evaluation of the antiplasmodial effect of retinol on plasmodium berghei berghei infection in mice	Oreagba A.I., Ashorobi R.B.	2006	Journal of Medical Sciences	6	5	None	Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria	Oreagba, A.I., Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Niger...	The present study was conducted to evaluate the antiplasmodial activity of retinol on chloroquine...	Antiplasmodial activity; Plasmodium berghei berghei; Retinol	chloroquine; pyrimethamine; retinol palmitate; animal experiment; animal model; antimalarial acti...	None	View
Scopus	2-s2.0-84855990038	Toxicological evaluation of the aqueous leaf extract of Moringa oleifera Lam. (Moringaceae)	Awodele O., Oreagba I.A., Odoma S., Teixeira Da Silva J.A., Osunkalu V.O.	2012	Journal of Ethnopharmacology	139	2	10.1016/j.jep.2011.10.008	Department of Pharmacology, College of Medicine, University of Lagos, Nigeria; Faculty of Agricul...	Awodele, O., Department of Pharmacology, College of Medicine, University of Lagos, Nigeria; Oreag...	Ethnopharmacological relevance: The rapid increase in consumption of herbal remedies worldwide ha...	Haematology; Liver and renal function; Moringa oleifera; Sub-chronic toxicity	creatinine; liver enzyme; Moringa oleifera extract; urea; animal experiment; animal tissue; artic...	None	View
Scopus	2-s2.0-67349248068	Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root e...	Adeyemi O.O., Akindele A.J., Ogunleye E.A.	2009	Journal of Ethnopharmacology	123	3	10.1016/j.jep.2009.03.023	Department of Pharmacology, College of Medicine, University of Lagos, P. M. B. 12003, Lagos, Nigeria	Adeyemi, O.O., Department of Pharmacology, College of Medicine, University of Lagos, P. M. B. 120...	Ethnopharmacological relevance: The aqueous root extract of Sanseviera liberica (Agavaceae), SL, ...	Antidiarrhoeal activity; Diarrhoea; Enteropooling; Gastric emptying; Intestinal transit; Sansevie...	alkaloid derivative; anthraquinone derivative; antidiarrheal agent; castor oil; isosorbide dinitr...	None	View
Scopus	2-s2.0-33749344765	Evaluation of the antidiarrhoeal activity of Byrsocarpus coccineus	Akindele A.J., Adeyemi O.O.	2006	Journal of Ethnopharmacology	108	1	10.1016/j.jep.2006.03.038	Department of Pharmacology, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria	Akindele, A.J., Department of Pharmacology, College of Medicine, University of Lagos, P.M.B 12003...	Based on its use in traditional African medicine, the antidiarrhoeal activity of the aqueous leaf...	Antidiarrhoeal; Byrsocarpus coccineus; Castor oil-induced diarrhoea; Intestinal transit	alpha 2 adrenergic receptor; Byrsocarpus coccineus extract; castor oil; isosorbide dinitrate; mor...	None	View
Scopus	2-s2.0-84873436922	Evaluation of analgesic and antistress potential of methanolic stem wood extract of Microdesmis p...	Okany C.C., Ishola I.O., Ashorobi R.B.	2012	International Journal of Applied Research in Natural Products	5	3	None	Department of Pharmacology, Faculty of Basic Medical Sciences, College of Medicine, University of...	Okany, C.C., Department of Pharmacology, Faculty of Basic Medical Sciences, College of Medicine, ...	Microdesmis puberula Hook.f. ex Planch (Pandaceae) is used in traditional African medicine in the...	Forced swimming test; Hot plate test; Immobilization; Microdesmis puberula; Mouse writhing test	acetylsalicylic acid; alkaloid derivative; analgesic agent; anthraquinone derivative; cardiac gly...	None	View
Scopus	2-s2.0-84873441546	Evaluation of the antinociceptive activities of the aqueous root extract of Alchornea cordifolia ...	Ishola I.O., Ashorobi R.B., Adeoluwa O.	2012	International Journal of Applied Research in Natural Products	5	3	None	Department of Pharmacology, Faculty of Basic Medical Sciences, College of Medicine, University of...	Ishola, I.O., Department of Pharmacology, Faculty of Basic Medical Sciences, College of Medicine,...	Alchornea cordifolia (Schumach and Thonn) Müll. Arg. (Euphorbiaceace) is used in traditional Afri...	Acute toxicity; Alchornea cordifolia; Hot plate; Mouse writhing; Tail clip	acetic acid; acetylsalicylic acid; alchornea cordifolia extract; antinociceptive agent; formaldeh...	None	View
Scopus	2-s2.0-84879658566	Psychological impact of cerebral palsy on families: The African perspective	Olawale O.A., Deih A.N., Yaadar R.K.K.	2013	Journal of Neurosciences in Rural Practice	4	2	10.4103/0976-3147.112752	Department of Physiotherapy, College of Medicine, University of Lagos, Lagos, Nigeria; Department...	Olawale, O.A., Department of Physiotherapy, College of Medicine, University of Lagos, Lagos, Nige...	Background: Psychological stress associated with cerebral palsy (CP) is known to be one of the mo...	Cerebral palsy; coping strategy; family; psychological stress	adolescent; adult; Africa; article; cerebral palsy; child; child care; coping behavior; cross-sec...	None	View
Scopus	2-s2.0-70350335319	Further evaluation of antihyperglycaemic activity of Hunteria umbellata (K. Schum) Hallier f. see...	Adeneye A.A., Adeyemi O.O.	2009	Journal of Ethnopharmacology	126	2	10.1016/j.jep.2009.08.037	Department of Pharmacology, Faculty of Basic Medical Sciences, Lagos State University College of ...	Adeneye, A.A., Department of Pharmacology, Faculty of Basic Medical Sciences, Lagos State Univers...	Ethnopharmacological relevance: In African traditional medicine, water decoction made from the dr...	Antihyperglycaemia; Antihyperlipidaemia; Experimental diabetes; Fasting insulin indices; Hunteria...	cholesterol; dexamethasone; fructose; glibenclamide; glucose; hemoglobin A1c; herbaceous agent; H...	None	View
Scopus	2-s2.0-84876042318	Evaluation of biochemical indices following administration of artemether, halofantrine and a comb...	Aprioku J.S., Obianime A.W.	2012	Journal of Applied Pharmaceutical Science	2	10	10.7324/JAPS.2012.21011	Department of Pharmacology, Faculty of Basic Medical Sciences, University of Port Harcourt, Port ...	Aprioku, J.S., Department of Pharmacology, Faculty of Basic Medical Sciences, University of Port ...	Combination of artemether and lumefantrine (artemether-lumefantrine) is an orally effective artem...	ACTs; Artemether-lumefantrine; Biochemical; Halofantrine; Lumefantrine	None	None	View
Scopus	2-s2.0-77955594922	Neuropharmacological evaluation of aridanin, a glycoside isolated from tetrapleura tetraptera fru...	Aderibigbe A.O., Iwalewa E.O., Adesina S.K., Ukponmwan O.E., Adebanjo A.O.	2007	Discovery and Innovation	19	3	None	Department of Pharmacology, Faculty of Health Sciences, University of Ilorin, Ilorin, Nigeria; De...	Aderibigbe, A.O., Department of Pharmacology, Faculty of Health Sciences, University of Ilorin, I...	The neuropharmacological effects of Aridanin - an N-acetylated glycoside isolated from Tetrapleur...	Aridanin; Central activities; Sedation; Tetrapleura tetraptera fruit	None	None	View
Scopus	2-s2.0-84886832354	Isolation of cycloeucalenol from boophone disticha and evaluation of its cytotoxicity	Adewusi E.A., Steenkamp P., Fouche G., Steenkamp V.	2013	Natural Product Communications	8	9	None	Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Private Bag X323,...	Adewusi, E.A., Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pr...	Boophone disticha (Amaryllidaceae) is widely used in traditional medicine in southern Africa. Sev...	Amaryllidaceae; Boophone disticha; Cycloeucalenol; Cytotoxicity; Regio-isomer; SH-SY5Y cells	cycloeucalenol; Amaryllidaceae; article; Boophone disticha; cell viability; column chromatography...	None	View
Scopus	2-s2.0-9644290819	Phytochemical screening and pharmacological evaluations for the antifertility effect of the metha...	Gebrie E., Makonnen E., Debella A., Zerihun L.	2005	Journal of Ethnopharmacology	96	42371	10.1016/j.jep.2004.08.026	Department of Pharmacology, Faculty of Medicine, Addis Ababa Univ., P.O. Box 9086, A., Ethiopia; ...	Gebrie, E., Department of Pharmacology, Faculty of Medicine, Addis Ababa Univ., P.O. Box 9086, A....	The practice of traditional medicine for the control of fertility in most parts of Ethiopia is ba...	Antifertility; Estrus cycle; Female rats; LD 50; Rumex steudelii extract; Secondary metabolites	plant extract; Rumex steudelii extract; unclassified drug; animal experiment; article; contracept...	None	View
Scopus	2-s2.0-73449090879	Evaluation of the analgesic properties of the Datura metel seeds aqueous extract	Wannang N.N., Ndukwe H.C., Nnabuife C.	2009	Journal of Medicinal Plants Research	3	4	None	Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos, Nigeria; Depar...	Wannang, N.N., Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos,...	This work was carried out to investigate the analgesic activity of dried seed of Datura metel Lin...	Analgesic; Antinociceptive; Datura metel; Seed extract	acetic acid; alkaloid derivative; anthraquinone derivative; carbohydrate derivative; cardiac glyc...	None	View
Scopus	2-s2.0-84878811197	Patient factors impacting antiretroviral drug adherence in a Nigerian tertiary hospital	Falang K.D., Akubaka P., Jimam N.S.	2012	Journal of Pharmacology and Pharmacotherapeutics	3	2	10.4103/0976-500X.95511	Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos/APIN Centre, Jo...	Falang, K.D., Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos/A...	Objective: To study the adherence levels and explore factors impacting them in out-patients on an...	Adherence; antiretroviral; HIV/AIDS; patients	antiretrovirus agent; acquired immune deficiency syndrome; adult; alcohol consumption; article; c...	None	View
Scopus	2-s2.0-42549157498	Effects of night-reading on daytime sleepiness, sleep quality and academic performance of undergr...	Adeosun S.O., Asa S.O., Babalola O.O., Akanmu M.A.	2008	Sleep and Biological Rhythms	6	2	10.1111/j.1479-8425.2008.00338.x	Department of Pharmacology, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife 220-005 Osun...	Adeosun, S.O., Department of Pharmacology, Faculty of Pharmacy, Obafemi Awolowo University, Ile-I...	We evaluated the impact of night reading on daytime sleepiness, quality of sleep and performance ...	Academic performance; Daytime sleepiness; PSQI; Sleep education; Sleep quality	academic achievement; adolescent; adult; article; controlled study; daytime somnolence; Epworth s...	None	View
Scopus	2-s2.0-70350304334	Pharmacological evaluation of oral hypoglycemic and antidiabetic effects of fresh leaves ethanol ...	Adeneye A.A., Agbaje E.O.	2008	African Journal Biomedical Research	11	1	None	Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos State, Niger...	Adeneye, A.A., Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lag...	In the present study, 50 - 400 mg/kg of body weight/day of 50% ethanol extract of the fresh leave...	Fresh leaf methanol extract; Hypoglycemia; Morinda lucida Benth.; Normal and Alloxan-induced diab...	Morinda lucida extract; oral antidiabetic agent; plant extract; tolbutamide; unclassified drug; a...	None	View
Scopus	2-s2.0-80051693441	Evaluation of the antipeptic ulcer activity of the leaf extract of Plantago lanceolata L. in rodents	Melese E., Asres K., Asad M., Engidawork E.	2011	Phytotherapy Research	25	8	10.1002/ptr.3411	Department of Pharmacology, School of Pharmacy, Addis Ababa University, King George VI Street, Ad...	Melese, E., Department of Pharmacology, School of Pharmacy, Addis Ababa University, King George V...	The effect of the leaf extract of Plantago lanceolata L. (Plantaginaceae) on gastric secretion an...	antisecretory; antiulcer; cytoprotection; Plantago lanceolata; rodents	acetic acid; antiulcer agent; indometacin; mercaptamine; misoprostol; mucilage extract; plant ext...	None	View
Scopus	2-s2.0-78649399126	Evaluation of in vivo antihypertensive and in vitro vasodepressor activities of the leaf extract ...	Ayele Y., Urga K., Engidawork E.	2010	Phytotherapy Research	24	10	10.1002/ptr.3141	Department of Pharmacology, School of Pharmacy, Addis Ababa University, P.O. Box 1176, Addis Abab...	Ayele, Y., Department of Pharmacology, School of Pharmacy, Addis Ababa University, P.O. Box 1176,...	The aim of this work was to evaluate the antihypertensive activity of the hydroalcohol extract of...	1K1C rat model; antihypertensive; hydroalcohol extract; Syzyguim guineense; vasorelaxation	adenosine triphosphate sensitive potassium channel; antihypertensive agent; cyclic GMP; histamine...	None	View
Scopus	2-s2.0-77958022441	Evaluation of the anticonvulsant activity of Zanthoxylum capense (Thunb.) Harv. (Rutaceae) in mice	Amabeoku G.J., Kinyua C.G.	2010	International Journal of Pharmacology	6	6	None	Department of Pharmacology, School of Pharmacy, University of the Western, Cape, Private Bag XI7,...	Amabeoku, G.J., Department of Pharmacology, School of Pharmacy, University of the Western, Cape, ...	The anticonvulsant activity of Zanthoxylum capense (Thunb.) Harv. (Rutaceae) was investigated by ...	Acute toxicity; Anticonvulsant activity; Leaf methanol and aqueous extracts; Phytochemical qualit...	alkaloid derivative; anticonvulsive agent; bicuculline; diazepam; dimethyl sulfoxide; gardenyl; m...	None	View

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