African Evaluation Database

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6600

Source

Scopus

Electronic ID

2-s2.0-45849146184

Authors

Roumy V., Hennebelle T., Zamblé A., Yao J.D., Sahpaz S., Bailleul F.

Title

Letter: Characterisation and identification of spermine and spermidine derivatives in Microdesmis keayana and Microdesmis puberula roots by electrospray ionisation tandem mass spectrometry and high-performance liquid chromatography/electrospray ionisation

Publication Year

2008

Source Title

European Journal of Mass Spectrometry

Volume

Issue

Citations

DOI

10.1255/ejms.910

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-45849146184&partnerID=40&md5=5e58c128cd23ec8189c777e78505d728

Affiliations

Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France; Laboratoire de Pharmacologie et Nutrition, Université de Cocody, Abidjan, BP 582, Abidjan 22, Côte d'Ivoire, South Africa

Authors with Affiliations

Roumy, V., Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France; Hennebelle, T., Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France; Zamblé, A., Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France; Yao, J.D., Laboratoire de Pharmacologie et Nutrition, Université de Cocody, Abidjan, BP 582, Abidjan 22, Côte d'Ivoire, South Africa; Sahpaz, S., Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France; Bailleul, F., Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, BP 83, F-59006 Lille Cedex, France

Abstract

Three new N1,N5,N14-tris(4- hydroxycinnamoyl)spermines were identified in hydromethanolic root extracts of Microdesmis keayana J. Léonard and Microdesmis puberula Hook f. The electrospray ionisation tandem mass spectrometry (ESI-MS/MS) technique with specific nuclear magnetic resonance analysis of hydrolysed products made it possible to identify N1,N5,N14-tris(p- coumaroyllspermine. N1-feruloyl,N5,N14-di(p- coumaroyl)spermine and N1,N5,N14-tris(feruloyl) spermine, named keayanines B, C and D, respectively. ESI-MS/MS analysis most effectively provided structural data although high-performance liquid chromatography/electrospray ionisation tandem mass spectrometry was also used to characterise four other compounds from Microdesmis puberula-keayanidines A, B, C and keayanine A - which had already been identified in M. keayana. This chemical data is the first to be published for M. puberula which is a commonly used plant in Central African traditional medicine. © IM Publications LLP 2008. All rights reserved.

Author Keywords

Keayanidine; Keayanine; Liquid-chromatography-mass-spectrometry; Microdesmis keayana; Microdesmis puberula; Spermidine; Spermine

Index Keywords

spermidine; spermine; article; chemistry; electrospray mass spectrometry; liquid chromatography; plant root; tandem mass spectrometry; traditional medicine; Chromatography, Liquid; Medicine, Traditional; Plant Roots; Spectrometry, Mass, Electrospray Ionization; Spermidine; Spermine; Tandem Mass Spectrometry

Funding Details

None