Gbore F.A., Adewole A.M., Oginni O., Oguntolu M.F., Bada A.M., Akele O.
Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Department of Microbiology, Adekunle Ajasin University, Akungba-Akoko, Nigeria
Gbore, F.A., Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Adewole, A.M., Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Oginni, O., Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Oguntolu, M.F., Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Bada, A.M., Department of Environmental Biology and Fisheries, Adekunle Ajasin University, Akungba-Akoko, Nigeria; Akele, O., Department of Microbiology, Adekunle Ajasin University, Akungba-Akoko, Nigeria
Fingerlings of Clarias gariepinus were used to evaluate the effect of dietary fumonisin B1 (FB1), a mycotoxin produced by Fusarium verticillioides, on growth, haematological and serum biochemical parameters. The fingerlings were sorted, weighed and randomly stocked in 16 plastic tanks at the rate of 20 fingerlings per tank. Fusarium-cultured maize grains containing FB1 were used to formulate three diets containing approximately 5.0, 10.0 and 15.0 mg FB1/kg, constituting diets 2, 3, and 4 respectively. These three diets, plus diet 1, which contained non-Fusarium cultured maize grains that served as the control, were used in a 6-week feeding trial. The final weight gains by the fingerlings were significantly (P∈<∈0.05) influenced by FB1. The final weights of the fingerlings fed diets 2, 3 and 4 ranged from 70.07 to 87.10% of the controls. The haematocrit, erythrocytes, haemoglobin, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and the serum protein constituents (total protein, albumin and globulin) values significantly (P∈<∈0.05) decreased, while the leucocytes, MCV and MCH increased significantly (P∈<∈0. 05) with increase in the dietary FB1. The total serum protein values of the fingerlings fed diets 2, 3 and 4 were 34.53, 39.42 and 50.17% lower than the total serum protein values of those fed the control diet. These results indicate that Fusarium-contaminated diets containing about 5.0 mg or more FB1/kg reduced weight gain and significantly altered haematological parameters and serum protein constituents in the fingerlings. These may have a significant impact on physiological activities and may be vital in immunosuppression in the fingerlings with a strong negative impact on subsequent performance of the fish. © 2010 Society for Mycotoxin Research and Springer.
albumin; fumonisin B1; globulin; hemoglobin; animal food; article; catfish; controlled study; erythrocyte; fingerling; food contamination; fungal contamination; Fusarium; fusarium verticillioides; growth rate; hematocrit; immune deficiency; leukocyte count; maize; mean corpuscular hemoglobin; mean corpuscular volume; nonhuman; weight gain; Clarias gariepinus; Fusarium; Gibberella moniliformis; Zea mays
